Dose Response Study of a Topical Formulation of Nitroglycerin for the Treatment of Raynaud's Phenomenon

• Status: Completed
• Trial end date: 2007-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this clinical study is to determine the response to two different dosage strengths of a topical nitroglycerin gel in patients with Raynaud's Phenomenon. Patient fingers will be monitored for changes in blood flow and skin temperature. Symptoms of pain, tingling and numbness will also be monitored.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: MediQuest Therapeutics
• Treatments: Nitroglycerin

Criteria

Inclusion Criteria:

• Patients with Raynaud's phenomenon

• Patients who are willing to discontinue any current therapies for Raynaud's phenomenon

Exclusion Criteria:

• The use of any medication containing nitroglycerin or known to interact with nitroglycerin

• Patients with a history of migraine or other severe headaches

• Open skin lesions or skin conditions in the area where medication is to be applied

• Pregnant or nursing women or those wishing to become pregnant.