Overview

Dose-escalation Study of Birinapant and Pembrolizumab in Solid Tumors

Status:
Terminated
Trial end date:
2020-02-17
Target enrollment:
Participant gender:
Summary
An ascending dose study in patients with solid tumors to evaluate the safety, tolerability, pharmacodynamics and efficacy of birinapant when given in combination with pembrolizumab. A dose expansion phase of 4 cohorts will also be included.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Medivir
TetraLogic Pharmaceuticals
Collaborator:
Merck Sharp & Dohme Corp.
Treatments:
Pembrolizumab