Dose-finding Study of Metformin With Chemoradiation in Locally Advanced Head and Neck Squamous Cell Carcinoma
Status:
Completed
Trial end date:
2020-02-21
Target enrollment:
Participant gender:
Summary
The purpose of this research study is to test the safety of adding metformin to standard of
care. The standard of care treatment will be cisplatin once every 3 weeks for 3 treatments
and radiation for 7 weeks.
Metformin is a medication that is currently used to treat diabetes. Increasing amounts of
metformin will be given to groups of patients already receiving normal treatment for their
cancer to see if metformin causes any good effects by killing your cancer or bad effects
(side effects).