Epidemiological studies have established a link between collisions while driving and cannabis
use. With the changing legal landscape around cannabis, there is much interest in determining
per se limits of cannabis while driving. The present study will evaluate driving on a driving
simulator after smoking placebo or cannabis with 3 different levels of THC. THC is the active
component in cannabis and blood, urine and oral fluid levels of THC will be correlated with
driving impairment.