Dosing Chart for Calculating the First Dose of Doxapram in Premature Infants
Status:
Completed
Trial end date:
2010-11-01
Target enrollment:
Participant gender:
Summary
Doxapram is used to stimulate respiration. For a given dose, the fluctuations in
concentrations observed in infants' blood may be wide, leading to a risk of lack of efficacy
or of toxic effects. Two factors are linked to these fluctuations: age and gender. The aim of
this study is to compare a dosage regimen based only on patient's weight, to another one
using a dosing chart taking into account weight, age and gender.
Phase:
Phase 4
Details
Lead Sponsor:
Jean Michel Hascoet Maternite Regionale Universitaire