Doubling the Iron Dose to Prevent IDA in Twin Pregnant Women

• Status: Completed
• Trial end date: 2020-08-01
• Target enrollment: 0
• Participant gender: Female

Summary

In twin pregnancies, the maternal iron demands are magnified, estimated at 1.8 times more than in singleton pregnancies due to greater maternal red blood cell mass and plasma volume expansion as well as increased fetal and placental requirements.

With a lack of randomized controlled trials assessing the adequacy of iron supplements on twin pregnancy, various recommendations are based on level 3 clinical expert opinions at most.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Ain Shams University
• Treatments: Iron

Criteria

Inclusion Criteria:

• Twin pregnancy.

• Hemoglobin ≥ 10.5 gm/d l. at booking visit

Exclusion Criteria:

• Continuous hyper-emesis gravid arum lasting beyond 20 weeks of gestation

• Thalassemia minor (alpha or beta).

• Mal-absorption disorders (such as inflammatory bowel diseases, Crohn's disease, ulcerative colitis, previous bowel resection).

• Anemia from chronic illness.

• Any use of multi-vitamin supplements containing iron.

• Any chronic blood loss. e.g: hemorrhoids.

• Autoimmune disorders.