Doxazosin Effects on ABPM in Hypertensive Patients With Diabetic Nephropathy
Status:
Completed
Trial end date:
2007-04-01
Target enrollment:
Participant gender:
Summary
Few studies have reported the effect of alpha1-adrenergic antagonists on 24-h blood pressure
and regulation of sympathetic nervous activity in hypertensive patients with diabetic
nephropathy. Using ambulatory blood pressure monitoring devices equipped with spectral
analysis of heart rate variability, we assess the effects of doxazosin on blood pressure in
diabetic nephropathy patients and compare the results with those in patients with essential
hypertension, patients with diabetes mellitus and patients with chronic nephropathy.