Doxazosin and Ramipril in Hypertension

• Status: Completed
• Trial end date: 2015-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Randomized double-blind parallel group study in patients with mild-to-moderate hypertension to evaluate the effects beyond the blood pressure lowering effect of treatment for 12 weeks with ramipril or doxazosin on hemostatic mechanisms and on endothelial function.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Karolinska Institutet
• Treatments: Doxazosin; Ramipril

Criteria

Inclusion Criteria:

• Primary mild-to-moderate hypertension

Exclusion Criteria:

• Pregnancy and lactation

• Recent (6 months) malignant disease or ongoing treatment for malignancy

• No absolute indication or contraindication for any of the study drugs