Doxycycline and Airway Inflammation in Chronic Obstructive Pulmonary Disease (COPD)
Status:
Unknown status
Trial end date:
2010-01-01
Target enrollment:
Participant gender:
Summary
COPD is a progressive pulmonary disease that is characterized by an inflammatory process in
the airways and the lungs which leads to progressive airway obstruction. The inflammation is
associated with tissue loss and remodelling. The investigators hypothesized that doxycycline
reduces neutrophilic airway inflammation in patients with COPD. Therefore the investigators
will conduct a randomized trial of doxycycline in 30 patients.
Phase:
Phase 4
Details
Lead Sponsor:
Medical Center Alkmaar
Collaborators:
Leiden University Medical Center Universiteit van Amsterdam University of Amsterdam