Doxycycline- and Furazolidone-containing Quadruple Regimen is Superior of Tailored Therapy

• Status: Unknown status
• Trial end date: 2019-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Doxycycline- and Furazolidone-containing Quadruple Regimen can be a successful rescue treatment for Helicobacter pylori Infection patients after Failure of several therapy. It is superior of tailored therapy as rescue treatment for helicobacter pylori Infection after failure of several therapy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sir Run Run Shaw Hospital
• Treatments: Anti-Bacterial Agents; Antibiotics, Antitubercular; Bismuth; Bismuth tripotassium dicitrate; Doxycycline; Esomeprazole; Furazolidone

Criteria

Inclusion Criteria:

1. A positive 13 C-urea breath test

2. Formal H.pylori treatment more than two times

3. Age >18 years

Exclusion Criteria:

1. Bismuth compounds, acid inhibitor, or antibiotics during 4 weeks before the patient is enrolled

2. Allergic to the medications

3. Upper gastrointestinal surgery history

4. Serious heart insufficiency, liver insufficiency, renal insufficiency and other serious medical problems

5. Evidence of blood dyscrasia

6. Pregnant and lactating women

7. Can't express his complain correctly and can't cooperate with the researcher