Doxycycline in the Treatment of Aggressive Periodontitis
Status:
Completed
Trial end date:
2014-12-08
Target enrollment:
Participant gender:
Summary
The aim of the study was to compare the clinical effects of systemic use of doxycycline to
amoxicillin plus metronidazole as adjunctive treatment in nonsurgical debridement of
aggressive periodontitis (AgP). Twenty four patients with aggressive periodontitis were
enrolled in this clinical study. They all received oral hygiene instruction and full-mouth
nonsurgical debridement using manual instruments. The test group received as adjunctive
antibiotic treatment 200 mg of doxycycline the first day followed by 100 mg per day during 14
days. The control group received 500 of amoxicillin and 250 of metronidazole, three times a
day for 7 days.