Dried Leaf Artemisia (DLA) Compared to Artemisinin Combination Therapy (ACT) vs Malaria
Status:
Withdrawn
Trial end date:
2019-10-01
Target enrollment:
Participant gender:
Summary
The overall goal is to validate efficacy and potential superiority of dried leaf Artemisia
annua (DLA) vs. artemisinin combination therapy (ACT) to cure malaria and to demonstrate
elimination of the transmission stage (gametocytes) of the disease. This is a 3 arm trial in
Democratic Republic of Congo covering 600 total adult and pediatric patients. Final
validation of infection from dried blood samples will be done at WPI.
Phase:
Phase 2
Details
Lead Sponsor:
Worcester Polytechnic Institute
Collaborators:
HEAL Africa Hospital, Goma, Democratic Republic of Congo Plesion International, Coatesville, PA Rwanguba Reference Hospital, Rwanguba, Democratic Republic of Congo
Treatments:
Artemether Artemether-lumefantrine combination Artemether, Lumefantrine Drug Combination Artemisinine Artemisinins Lumefantrine