Drug-Drug Interaction Study Between Telaprevir and Buprenorphine
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The purpose of this study is to investigate the drug-drug interaction potential between
telaprevir and buprenorphine/naloxone. An understanding of the interaction potential will
help to determine whether buprenorphine dose adjustments are necessary for patients who are
concomitantly treated with telaprevir.
Telaprevir, in combination with other antiviral agents, is being investigated for the
treatment of chronic hepatitis C virus infection. Buprenorphine/naloxone is used for
maintainance therapy in patients with opioid dependence.
Phase:
Phase 1
Details
Lead Sponsor:
Vertex Pharmaceuticals Incorporated
Collaborator:
Tibotec BVBA
Treatments:
Buprenorphine Buprenorphine, Naloxone Drug Combination Naloxone