Drug - Drug Interaction Study of Quinine Sulfate and Ciprofloxacin
Status:
Completed
Trial end date:
2008-10-01
Target enrollment:
Participant gender:
Summary
Ciprofloxacin is moderate inhibitor of cytochrome P450 1A2 (CYP1A2), one of the enzymes
responsible for the metabolism of quinine. This study will evaluate the effect of
ciprofloxacin-related inhibition of CYP1A2 on the pharmacokinetics of quinine sulfate.