Drug-drug Interaction Between Simvastatin and SHR3824

• Status: Unknown status
• Trial end date: 2017-12-08
• Target enrollment: 0
• Participant gender: Male

Summary

the purpose of thr study is to investigate the potential interation between multiple oral doses of SHR3824 and single oral dose of Simvastatin in healthy adult volunteers.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Jiangsu HengRui Medicine Co., Ltd.
• Treatments: Simvastatin

Criteria

Inclusion Criteria:

• Healthy male volunteers with a body mass index (BMI, a measure of a person's weight in relation to height) between 19 and 26 kg/m2

Exclusion Criteria:

• History of hypoglycemia

• History of urinary tract infections,or genital infections

• History of current clinically significant medical illness as determined by the Investigator

• Known allergy to SHR3824 or Simvastatin or any of the excipients of the formulation of SHR3824 or Simvastatin