Drug-drug Interactions Between AZD4205 and Itraconazole/Carbamazepine
Status:
Recruiting
Trial end date:
2023-04-18
Target enrollment:
Participant gender:
Summary
This is a Phase 1, single-center, nonrandomized, open-label, 2-part, fixed-sequence,
drug-drug interaction (DDI) study to assess the effect of multiple doses of itraconazole, a
CYP3A4 enzyme inhibitor, on the single dose PK of AZD4205 in healthy adult subjects (Part A)
and to assess the effect of multiple doses of carbamazepine, a CYP3A4 inducer, on the single
dose PK of AZD4205 in healthy adult subjects (Part B).