Dual Trigger" in IVF Patients at High Risk of Ovarian Hyper Stimulation Syndrome
Status:
Recruiting
Trial end date:
2023-12-31
Target enrollment:
Participant gender:
Summary
The present study aims to evaluate whether the use of a "dual trigger" can improve IVF
outcomes, compared to GnRH agonist (GnRH-a) alone, in patients at high risk of OHSS
undergoing a freeze-all cycle. By examining freeze-all cycles with frozen embryo transfer(s)
(FET) only, we eliminate the potential confounding issue of inadequate luteal support to the
endometrium and focus primarily on the effect of a "dual trigger" on oocyte quality and
embryo potential.
To our best knowledge, there have been no randomized, controlled trials conducted to address
this hypothesis.