Cellulitis is among the most common infections leading to hospitalization, yet the optimal
duration of therapy remains ill defined. Pragmatically, Dutch guidelines advise 10-14 days of
antibiotics, which is the current standard of care. Recently it has been shown that
antibiotic treatment for pneumonia and urinary tract infections can safely and significantly
be shortened. Importantly, in an outpatient setting, treatment of uncomplicated cellulitis
with 5 days of antibiotics was as effective as 10 days. We hypothesize that there is no
difference in outcomes when patients hospitalized with cellulitis are treated with either a
short-course (6 days) or standard-course (12 days) of antibiotics.
Phase:
Phase 4
Details
Lead Sponsor:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Collaborator:
ZonMw: The Netherlands Organisation for Health Research and Development