Duration of Leg Nerve Blocks With Dexamethasone Added to Local Anesthetic

• Status: Withdrawn
• Trial end date: 2013-08-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a Randomized Double blinded controlled trial on the effect of adding dexamethasone to Ropivacaine on the duration of pain relief for ultrasound guided femoral, obturator and popliteal block after total knee replacement surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of New Mexico
• Treatments: BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Ropivacaine

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists physical status I to III,

• Aged 18 and above,

• Undergoing total knee replacement.

Exclusion Criteria:

• Body mass index of more than 45 kg/m2 (higher chance of failure)

• Weight less than 70 kg

• Diabetes

• Injection site deformities

• Infection at the injection site

• Existing peripheral neuropathy

• Allergy to LA agents

• Contraindications to dexamethasone

• Patients with severe PONV

• Patients with peptic ulceration or upper GI bleed of unknown origin

• Coagulopathy

• Any other contraindication to lower limb peripheral nerve block