Overview

Durvalumab and Tremelimumab Combination in Somatically Hypermutated Recurrent Solid Tumors

Status:
Recruiting
Trial end date:
2024-06-01
Target enrollment:
Participant gender:
Summary
This study will examine whether patients with relapsed/refractory solid tumors harboring evidence of somatic hypermutation (intermediate versus high tumor mutational burden) will exhibit improvement in disease progression-free survival with dual Tremelimumab and Durvalumab treatment.
Phase:
Phase 2
Details
Lead Sponsor:
John L. Villano, MD, PhD
Treatments:
Antibodies, Monoclonal
Durvalumab
Tremelimumab