Dydrogesterone in the Treatment of Endometrial Polyps

• Status: Completed
• Trial end date: 2019-12-31
• Target enrollment: 0
• Participant gender: Female

Summary

This study is intended to observe the therapeutic effect of dydrogesterone on endometrial polyps and provide a reference for clinical treatment.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Peking Union Medical College Hospital
• Treatments: Dydrogesterone

Criteria

Inclusion Criteria:

1. women of childbearing age from 20 to 50 years old

2. with or without menstrual changes:

1. menostaxis (longer than 7 days)

2. shortened menstrual cycles(less than 23 days)

3. menorrhagia(more than twice as much as usual)

4. abnormal vaginal bleeding(non-menstrual vaginal bleeding)

3. with following signs of vaginal ultrasound in the follicular phase (day 1 to day 10 of a menstrual cycle):

1. typical signs with a suspect of EP: (median/high) echo with a regular contour within the uterine lumen;

2. atypical signs with a suspect of EP: punctate cystic areas within the endometrium and the endometrial thickness >1cm;

Exclusion Criteria:

1. no menses within half a year;

2. surgery or drug treatment of endometrial lesions in the past half year;

3. with current intrauterine device;

4. combined with other acute gynecological inflammation;

5. with clinically suspected malignant tumors;

6. long-term use of oral contraceptives;

7. with abnormal liver and kidney function;

8. with benign or malignant breast tumors;

9. with any systemic malignant tumor or a history of tumors;

10. participants who are pregnant.