Overview

ED50 and ED95 of Intrathecal Bupivacaine With or Without Epinephrine for Total Knee Replacement Arthroplasty

Status:
Completed
Trial end date:
2011-01-01
Target enrollment:
0
Participant gender:
All
Summary
This prospective randomized double-blind dose-response study is aimed to investigate the ED50 and ED95 of intrathecal bupivacaine with or without epinephrine 100 mcg for total knee replacement arthroplasty.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Seoul Medical Center
Treatments:
Bupivacaine
Epinephrine
Epinephryl borate
Racepinephrine
Criteria
Inclusion Criteria:

- The patients with ASA class I or II scheduled for total knee replacement surgery

Exclusion Criteria:

- Patients with previous spine surgery, diabetic and other neuropathy, skin infection at
the site of injection, allergy to bupivacaine and other common contraindications for
spinal anesthesia were excluded from this study.