ED90 of Norepinephrine and Phenylephrine Boluses Under Intensive Treatment

• Status: Not yet recruiting
• Trial end date: 2025-06-30
• Target enrollment: 0
• Participant gender: Female

Summary

The objective of this study is to investigate the ED90 of norepinephrine and phenylephrine boluses for treating postspinal anesthesia hypotension under intensive treatment during cesarean section

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: General Hospital of Ningxia Medical University
• Treatments: Norepinephrine; Oxymetazoline; Phenylephrine; Vasoconstrictor Agents

Criteria

Inclusion Criteria:

• 18-45 years

• Primipara or multipara

• Singleton pregnancy ≥37 weeks

• American Society of Anesthesiologists physical status classification I to II

• Scheduled for cesarean section under spinal anesthesia

Exclusion Criteria:

• Body height < 150 cm

• Body weight > 100 kg or body mass index (BMI) ≥ 40 kg/m2

• Eclampsia or chronic hypertension or baseline blood pressure ≥180 mmHg

• Hemoglobin < 7g/dl

• Fetal distress, or known fetal developmental anomaly