EEG Studies of IV Methylphenidate-Induced Emergence From Anesthesia

• Status: Withdrawn
• Trial end date: 2019-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to test the hypothesis that methylphenidate actively induces emergence from propofol and sevoflurane general anesthesia in healthy volunteers.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Massachusetts General Hospital
• Treatments: Anesthetics; Methylphenidate; Propofol; Sevoflurane

Criteria

Inclusion Criteria:

1. Age 18-36 years

2. ASA classification 1 or 2

3. Normal body weight, BMI ≤ 30

4. Non-smoker

5. Right handed

6. No history of taking stimulants

Exclusion Criteria:

• In general, patients will be excluded from the study if the state of their chronic health problems gives them an ASA physical status classification of 3 or beyond.