EEG Study of IV Methylphenidate-Induced Emergence From Propofol Sedation
Status:
Withdrawn
Trial end date:
2021-11-01
Target enrollment:
Participant gender:
Summary
The investigators are performing this research study to find out if intravenous (IV)
methylphenidate (commonly known as Ritalin) can help people recover faster from propofol
sedation. The investigators also want to know how IV methylphenidate acts in the brain and
whether IV methylphenidate is safe to take with an anesthetic (a drug or agent used to
decrease or eliminate the feeling of pain by causing unconsciousness) without causing too
many side effects. The brain's electrical activity will be studied and recorded using a
machine called an electroencephalogram (EEG).
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Massachusetts General Hospital
Treatments:
Anesthetics Methylphenidate Molecular Mechanisms of Pharmacological Action Propofol