Overview

EGFR Inhibition Using Weekly Erlotinib for Recurrent Malignant Gliomas

Status:
Completed
Trial end date:
2018-12-31
Target enrollment:
Participant gender:
Summary
The purpose of this study is to test the effectiveness of a drug called erlotinib in treating the tumor. This is a multi-center pilot study that explores efficacy and molecular effects of high dose weekly erlotinib for recurrent EGFR vIII mutant malignant gliomas, and correlate molecular profile of pre-treatment tissue with outcome.
Phase:
Phase 1
Details
Lead Sponsor:
Andrew B Lassman, MD
Andrew Lassman
Collaborators:
Genentech, Inc.
OSI Pharmaceuticals
Treatments:
Erlotinib Hydrochloride