Overview

EPOCH Chemotherapy and Bortezomib for Associated T-Cell Leukemia Lymphoma

Status:
Completed
Trial end date:
2016-04-01
Target enrollment:
Participant gender:
Summary
The rationale of the current study is to explore the use of combination chemotherapy together with antiretroviral agents in order to determine the efficacy and toxicity of this approach, while also examining markers of virus replication and expression, and tumor cell proliferation to gain understanding of the biological basis of this malignancy and to identify predictors of response.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Washington University School of Medicine
Treatments:
Bortezomib
Cyclophosphamide
Doxorubicin
Etoposide
Etoposide phosphate
Liposomal doxorubicin
Prednisone
Raltegravir Potassium
Vincristine