EXtending the tIme Window of Thrombolysis by ButyphThalide up to 6 Hours After Onset (EXIT-BT)
Status:
Not yet recruiting
Trial end date:
2022-12-30
Target enrollment:
Participant gender:
Summary
To date, the time window of intravenous thrombolysis is limited within 4.5 hours of stroke
onset. Although EXTEND study has proved that intravenous thrombolysis can be extended from
4.5 to 9 hours, but the eligible patients must be selected by CTP. Thus, it is of clinical
importance how to extend the time window of intravenous thrombolysis, which can benifit more
patients. The current trial aims to investigate the effect of intravenous thrombolysis with
TNK from 4.5 to 6 hours in ischemic stroke with help of Butyphthalide, which was found to be
neuroprotective.