Overview

Early ART to Limit Infection and Establishment of Reservoir

Status:
Active, not recruiting
Trial end date:
2023-09-08
Target enrollment:
Participant gender:
Summary
The study is being done to: - start ART early in those recently or acutely infected with HIV-1 - see how starting ART as soon as the infection is found affects the amount of HIV-1 in blood and how well the body fights the HIV-1 infection - look at the amount of HIV-1 DNA (genetic material for HIV-1) seen in CD4+ T-cells (infection-fighting cells in blood) after 48 weeks of ART - see how early treatment for HIV affects the numbers of HIV-1 infection fighting cells (CD4+ and CD8+ T-cells) in blood
Phase:
Phase 2
Details
Lead Sponsor:
AIDS Clinical Trials Group
Collaborator:
National Institute of Allergy and Infectious Diseases (NIAID)
Treatments:
Anti-Retroviral Agents
Cobicistat
Elvitegravir
Emtricitabine
Emtricitabine tenofovir alafenamide
Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination
Tenofovir