Early Bolus Surfactant Replacement Therapy Versus Standard Care in Term Neonates With Meconium Aspiration Syndrome

• Status: Recruiting
• Trial end date: 2024-03-12
• Target enrollment: 0
• Participant gender: All

Summary

The objective of the study is to compare the total duration of respiratory support in term neonates (≥37weeks) with meconium aspiration syndrome, who are provided early(≤2hr) bolus surfactant therapy versus standard care.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Lady Hardinge Medical College
• Treatments: Pulmonary Surfactants

Criteria

Inclusion Criteria:

• Gestation age ≥ 37 week

• Cephalic presentation

• Singleton pregnancy

• Age < 2 hours

• Baby delivered through meconium stained amniotic fluid

• Presence of respiratory distress (DOWNE's score ≥4)

Exclusion Criteria:

• Major congenital malformation

• Antenatal diagnosed CHD

• Hydrops fetalis

• Air leaks before enrolment