Early Diagnosis of Asthma in Young Children

• Status: Completed
• Trial end date: 2012-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The overall aim of the study is an early asthma diagnosis in young children by the use of non-invasive biomarkers of airway inflammation /oxidative stress in exhaled air, and early lung function measurements

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Maastricht University Medical Center
• Collaborators: Stichting Astma Bestrijding, The Netherlands; The Netherlands Asthma Foundation

Criteria

Inclusion Criteria:

• Children aged 2-3 years, with recurrent respiratory symptoms suggestive of asthma

• Children aged 2-3 years, with no or minor respiratory symptoms

Exclusion Criteria:

• Mental retardation

• Cardiac anomalies

• Congenital malformations

• Other diseases of the lungs/airways

• Chronic systemic inflammatory diseases like M. Crohn

• The inability to perform lung function measurements and/or exhaled air collection