Early Diagnosis of Diastolic Dysfunction and Reliability of DSE in Detecting Stress Diastolic Dysfunction
Status:
Completed
Trial end date:
2011-01-01
Target enrollment:
Participant gender:
Summary
The heart becoming "stiff" due to increased fibrous tissue or decreased elasticity of the
heart tissue is one of the earliest changes caused by heart failure. These changes can be
detected by simple non-invasive echocardiogram techniques. However, these techniques usually
detect the increased "stiffness" of the heart only after it has progressed to a significant
extent. The investigators hypothesize that if they stress the heart using a Dobutamine
infusion and measure the filling pressure using echocardiogram, it will provide them with
tools to identify these changes earlier.
Phase:
N/A
Details
Lead Sponsor:
University of Missouri-Columbia
Collaborators:
Kansas City Veteran Affairs Medical Center Veterans Administration, Kansas City