Overview

Early-Line Anti-EGFR Therapy to Facilitate Retreatment for Select Patients With mCRC

Status:
Recruiting
Trial end date:
2025-10-01
Target enrollment:
Participant gender:
Summary
The study will use previously established doses of panitumumab or cetuximab in the metastatic setting for the treatment of unresectable colorectal cancer (CRC). It is designed to investigate an alternative treatment strategy to maximize the benefit to inhibition of epidermal growth factor receptor (EGFR) for a highly selected patient population. It will enroll 110 participants with left-sided, unresectable metastatic CRC. Participants will be on study up to 5 years.
Phase:
Phase 2
Details
Lead Sponsor:
University of Wisconsin, Madison
Collaborator:
Doris Duke Charitable Foundation
Treatments:
Cetuximab
Irinotecan
Panitumumab