Early Non-Ablative Fractional Laser Resurfacing for Acne Scars After Treatment With Oral Isotretinoin

• Status: Completed
• Trial end date: 2017-06-14
• Target enrollment: 0
• Participant gender: All

Summary

Patients who have completed have completed a cumulative dose of >=120miligram/kilogram oral isotretinoin within the last 30 days, and has mild to moderate acne scarring will be randomized, into a right-left comparison study using Fraxel DUAL (Solta Medical) laser on one side of the face, and no treatment on the other side of the face. Subejcts will receive treatments at week 0, week 4, and week 8. Photographs will be taken after each treatment, 7 days after each treatment, and 4 months after last treatment. Photographs will be reviewed by blind assessors who will analyze the pre- and post-treatment photographs to measure change.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: David Smart
• Treatments: Isotretinoin; Valacyclovir

Criteria

Inclusion Criteria:

• 18 years or older

• Completed cumulative dose of >=120 miligram/kilogram oral isotretinoin within the last 30 days

• Mild-moderate acne scarring of all types (icepick, boxcar, rolling)

Exclusion Criteria:

• Pregnant or nursing women

• History of porphyria, allergy to porphyrins, or photodermatosis

• Active infectious disease

• Severe acne scarring

• Propensity to hypertrophic or keloid scarring

• Immunosuppression

• Laser or any cosmetic treatment in the previous 6 months