Early Rehabilitation After Hip Fracture

• Status: Unknown status
• Trial end date: 2008-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to compare a low versus high intensity physiotherapy early rehabilitation program combined with a low versus high dose vitamin D early rehabilitation program in a randomized controlled trial among elderly patients with acute hip fracture in an acute care setting. The primary outcome to be compared between treatment arms is the rate of falls during a 12-month follow-up. Secondary outcomes are injurious falls, number of persons who fell, low-trauma fractures (at the hip, forearm, humerus, pelvis, ankle, spine, femur, tibia), disability, quality of life (Euro-Qol), mortality and health care utilization. Another secondary outcome will be admission to nursing home compared between treatment arms among subjects, who are community-dwelling prior to the index hip fracture. Admission to nursing home is the marker of loss of independence for the individual, but also triggers high cost for the society.

The study will provide new early rehabilitation guidelines to allocate health care resources efficiently in the acute care setting. Eventually and most importantly, the study will help improve outcomes in patients with hip fractures.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Swiss National Science Foundation
• Treatments: Cholecalciferol; Vitamin D

Criteria

Inclusion Criteria:

• Age 65 years or older

• Acute hip fracture admitted to one hospital center

Exclusion Criteria:

• A Folstein Mini Mental Score of less than 15 as an indicator of significant dementia

• Primary hyperparathyroidism

• Current cancer with wasting or bone metastases

• Hyperparathyroidism

• Sarcoidosis

• A kidney stone in the past 5 years or significant renal disease (creatinine clearance below 15 ml/min)

• Hypercalcemia (albumin adjusted) of more than 2.8 mmol/l

• non-surgical treatment

• no German language skills

• severe hearing or visual impairment