Early Treatment Stratification Based on PET Scan Response to Chemotherapy in Patients With Diffuse Large B-cell Lymphoma
Status:
Completed
Trial end date:
2012-09-01
Target enrollment:
Participant gender:
Summary
The aim of the study is to evaluate the event free survival at three years in patients with
diffuse large B-cell lymphoma with poor prognostic factors receiving R-MegaCHOP as induction
therapy. Patients with positive PET after three cycles of R-MegaCHOP receive early salvage
treatment with R-IFE and autologous stem cell transplantation. Patients with negative PET
after three cycles of R-MegaCHOP are treated with three additional cycles of R-MegaCHOP
without transplant.
Phase:
Phase 2
Details
Lead Sponsor:
Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea