Early Use of Vasopressin in Post-Fontan Management

• Status: Completed
• Trial end date: 2019-01-28
• Target enrollment: 0
• Participant gender: All

Summary

This is an investigator initiated, prospective, single-center, double-blinded, randomized, placebo-controlled trial of post-operative low dose vasopressin infusions as an early treatment of low systemic perfusion in pediatric patients following Fontan palliation.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Medical College of Wisconsin
• Treatments: Arginine Vasopressin; Vasopressins

Criteria

Inclusion Criteria:

• Planned completion of Fontan palliation

• English or Spanish speaking

• Completion of Informed Consent

Exclusion Criteria:

• Previous failed attempts at Fontan completion with subsequent takedown

• Planned concomitant atrioventricular valvuloplasty or neoaortic valve or arch reconstruction at the time of Fontan completion

• History of renal failure requiring renal replacement therapy

• Absence of informed consent