Echocardiographic and Arterial Pressure Waveform Changes After Reducing Heart Rate With Esmolol in Septic Shock Patients
Status:
Completed
Trial end date:
2014-06-01
Target enrollment:
Participant gender:
Summary
Clinical study suggests that beta-blockers by decreasing heart rate together with an increase
in stroke volume do not negatively affect cardiac output allowing an economization of cardiac
work and oxygen consumption in patients with septic shock. Whether this hemodynamic profile
leads to an amelioration of myocardial performance is still unclear. The objective of the
present study is therefore to elucidate whether a reduction in heart rate with esmolol is
associated to an improvement of cardiac efficiency in patients with septic shock who remained
tachycardic after hemodynamic optimization.