Education, Counseling, and Drug Therapy to Reduce Symptoms of Metabolic Syndrome

• Status: Completed
• Trial end date: 2014-04-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will determine the effects of a supplement in reducing symptoms of metabolic syndrome, a collection of symptoms that increase the risk for developing heart disease, stroke, and diabetes.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Oregon Health and Science University
• Collaborator: National Center for Complementary and Integrative Health (NCCIH)

Criteria

Inclusion Criteria:

• Body mass index (BMI) between 30 and 45

• Live in the Portland, Oregon metropolitan area

• Willing and able to complete a 12-week weight loss program

• Meet at least 3 of the following 5 criteria: 1) waist circumference greater than 40 inches for men and 35 inches for women; 2) fasting triglycerides higher than 150 mg/dl; 3) high density lipoprotein (HDL) lower than 40 mg/dl for men and 50 mg/dl for women; 4) systolic blood pressure (BP) of 130 mmHg or higher or diastolic BP of 85 mmHg or higher; 5) fasting glucose of 100 mg/dl or higher

Exclusion Criteria:

• Any medications, including dietary supplements, that could interfere with the study

• Medical conditions contraindicating a diet and exercise weight loss program

• History of congestive heart failure, stroke, myocardial infarction, coronary artery bypass graft, or atherosclerotic cardiovascular disease

• Current diagnosis of cancer

• Hospitalization for a psychiatric condition within 12 months prior to study entry

• Weight loss medications within 6 months prior to study entry

• Change in body weight greater than 5% within 6 months prior to study entry

• Consumption of more than 21 alcoholic drinks per week

• Current participation in another clinical trial OR living in the same household with another participant in this study

• Currently exercising for more than 30 minutes, 3 times per week

• Fasting blood glucose higher than 125 mg/dl

• BP higher than 145/90

• Triglycerides higher than 500 mg/dl

• Training as a health care provider or health scientist

• Pregnancy or breastfeeding