Effect Of A Locally Delivered Probiotic Sacchraomyces Boulardii In The Management Of Chronic Periodontitis
Status:
Completed
Trial end date:
2018-03-26
Target enrollment:
Participant gender:
Summary
This study was carried out in the Department of Periodontology and source of patient was be
from the outpatient section of Tatyasaheb Kore Dental College & Research Centre, New Pargaon.
Study included the 31 patients with chronic periodontitis, with age group between 35-60
years, two interdental suprabony pockets with 5-8mm pocket depth in two different quadrants
were chosen as the test site (TS) and control sites (CS). In control sites, only SRP was
performed followed by placement of placebo distilled water. In test sites, SRP was followed
by placement of Lyophilized saccharomyces boulardii in the pocket. S. boulardii will be
delivered subgingivally by by mixing 1gm of sachet containing 250mg of lyophilized yeast with
0.5ml of distilled water this prepared paste was injected in the perio pocket with luer lock
syringe and cannula .The subgingival plaque samples were collected at baseline, 4th day, 4
week for detection of p. gingivalis for microbiological analysis and clinical parameters
wiere recorded at baseline and at 1 month.