Effect Of CP-690,550 On The Pharmacokinetics Of Metformin In Healthy Volunteers

• Status: Completed
• Trial end date: 2011-07-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will evaluate the potential effect of CP 690,550 on the pharmacokinetics of metformin, a probe drug for organic cationic transport.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Pfizer
• Treatments: Metformin; Tofacitinib

Criteria

Inclusion Criteria:

• Adult healthy male and/or female (of non child bearing potential) subjects.

Exclusion Criteria:

• Subjects with clinically significant systemic and laboratory abnormalities.

• Subjects with clinically significant infections within the past 3 months.

• Women of child-bearing potential.