Effect Site Controlled, Reaction Time Safeguarded, Patient Maintained Sedation With Propofol in Healthy Volunteers

• Status: Completed
• Trial end date: 2006-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Whether patient-maintained sedation (the patient controls his/her degree of sedation using a hand-held device) using the drug propofol is safer and more effective when using deteriorating reaction time as an added safeguard against the small potential for over sedation in a group of healthy volunteers.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Sonia Allam
• Collaborator: NHS Greater Glasgow and Clyde
• Treatments: Propofol

Criteria

Inclusion Criteria:

• ASA I or II (healthy or mild systemic illness) healthy volunteers

• Age 18 - 50

Exclusion Criteria:

• ASA III or above

• Out with age group above

• Contraindication to propofol

• History of epilepsy

• History of substance abuse

• Major Psychiatric illness

• Pregnancy or breastfeeding

• Unable or unwilling to give informed consent

• Unable to use necessary apparatus

• Vulnerable groups