Effect iNO on Functional Respiratory Imaging in Subjects With WHO Group 3 Pulmonary Hypertension With COPD on Oxygen
Status:
Terminated
Trial end date:
2017-08-21
Target enrollment:
Participant gender:
Summary
The objective of this exploratory study is to examine the utility of high resolution computed
tomography (HRCT) to measure changes in functional pulmonary imaging parameters as a function
of long term iNO administrationusing the device INOpulse for 4 weeks in relation to Patient
Reported Outcome (PRO) and exercise tolerance in subjects with WHO Group 3 PH associated with
COPD on LTOT.
Changes from baseline to 4 weeks of pulsed iNO and after 2 weeks of withdrawal from pulsed
iNO will be evaluated.