The purpose of this study is to determine whether atorvastatin 80mg can reduce the
development of myocardial edema following coronary artery bypass surgery.
This study also want to determine:
1. whether atorvastatin 80mg can influence Follistatin-like 1 (FSTL1) plasma level
following bypass surgery?
2. whether there is correlation between myocardial edema and FSTL1 plasma level?
3. the efficacy of atorvastatin 80mg compared to atorvastatin 10mg in reducing hs-CRP (high
sensitive-C reactive protein) and MDA (malondialdehyde) plasma level following bypass
surgery?
4. the efficacy of atorvastatin 80mg compared to atorvastatin 10mg in raising PKA and PKB
plasma level following bypass surgery?
Phase:
Phase 3
Details
Lead Sponsor:
National Cardiovascular Center Harapan Kita Hospital Indonesia