Effect of Acetylcholinesterase Inhibitors on the Gait of the Patients With Parkinson Disease
Status:
Unknown status
Trial end date:
2018-12-30
Target enrollment:
Participant gender:
Summary
Cholinergic deficiency in the brain can be related to gait and balance problems in Parkinson
disease (PD). Recent clinical trials suggested a beneficial role of acetylcholinesterase
inhibitors (AchEI) on gait in PD. In this study, the investigators are planning to study the
influence of AchEI on a brain network for gait and balance in PD. As gait problem is
prominent in postural instability and gait disturbance (PIGD) subtype, this study will focus
on the patients with PIGD phenotype.