Effect of Acid Blockade on Microbiota and Inflammation in Cystic Fibrosis (CF)
Status:
Terminated
Trial end date:
2018-01-18
Target enrollment:
Participant gender:
Summary
Mucus in the airways of patients with CF represents an area for bacteria proliferation,
microbial infection and inflammation. Similar to the lung, the esophagus provides an
environment for bacterial to grow. The overall goal of this proposal is to characterize the
esophageal microbiota of children with CF that are treated or untreated with acid blockade
medication and to measure its possible impact on respiratory disease to develop novel
treatment strategies.
Details
Lead Sponsor:
University of Colorado, Denver
Collaborators:
Cystic Fibrosis Foundation Cystic Fibrosis Foundation Therapeutics