Effect of Add-on Montelukast to Inhaled Corticosteroids on Airway Responsiveness
Status:
Completed
Trial end date:
2006-10-01
Target enrollment:
Participant gender:
Summary
Leukotriene receptor antagonists appear to posses additive anti-inflammatory effects to the
effect of inhaled corticosteroids.
Hypothesis: Treatment with oral montelukast will lower the dose-response plateau to inhaled
methacholine in patients with mild to moderate persistent asthma treated with a stable dose
of inhaled corticosteroids.