Effect of Addition of Mannitol to Bupivacaine on IANB Success and Post-endodontic Pain

• Status: Completed
• Trial end date: 2014-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Inferior alveolar nerve block using either 0.5% bupivacaine alone or in addittion to mannitol in patients with irreversible pulpitis in mandibular molars.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cairo University
• Treatments: Bupivacaine; Mannitol

Criteria

Inclusion Criteria:

1. Adult patients; age between 17-35 years old.

2. Males or Females.

3. Medically-free patients

4. Patients suffering from symptomatic irreversible pulpitis without apical periodontitis in mandibular molar teeth.

5. Positive patients' acceptance for participation in the study.

Exclusion Criteria:

• Patients who had any analgesic during proceeding 12 hours before the treatment.

• Teeth with necrotic, infected pulp, swelling or symptomatic apical periodontitis (apical abscess).

• Pregnant females.

• Patients with history of significant medical conditions (contraindication of mannitol use).

• Addiction

• Psycological disturbance.