Overview

Effect of Adrenaline Concentration on Intraoperative Hemodynamics of Liposuction Patients

Status:
Not yet recruiting

Trial end date:
2023-10-15

Target enrollment:
0

Participant gender:
All

Summary

Liposuction is a procedure that has emerged over the last 30 years as a method to remove subcutaneous fat for cosmetic purposes. Numerous liposuction techniques have been developed .Tumescent liposuction involves using large volumes of dilute local anesthetic and epinephrine to facilitate anesthesia and decrease blood loss. Questions remain about the appropriate dose of local anesthetic, the use of general anesthesia in liposuction, and the setting in which the chosen liposuction method is used. Adrenaline is the most commonly used vasoconstrictor, the recommended concentration in the tumescent solution is 0.25-1 mg/L depending on the tissue vascularity. In the more vascular tissues, the concentration is 1 mg/L and is decreased to 0.5 mg/L in the less vascular areas of the body. The dose should not exceed 50μg/kg. If the maximum dose is anticipated to exceed, the procedure should be done in several stages.

Phase:

Phase 3

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Al-Azhar University

Collaborator:

Benha University

Treatments:

Epinephrine
Epinephryl borate
Racepinephrine

Criteria

Inclusion Criteria:

- ASA I patients

- scheduled for liposuction for abdomen and flanks and body contouring with liposuction

Exclusion Criteria:

- Bleeding disorders, anemia or hemoglobin level less than 11g/dl

- Cardiovascular diseases,

- Uncontrolled diabetes mellitus,

- Collagen disorders, and

- Pregnancy