Healthy African American subjects with normal hepatic and renal function will be administered
10mg adefovir dipivoxil in a fasting state. Subjects will have blood and urine collections
over the following 24 hours for the measurement of adefovir renal clearance. To investigate
the role of age in renal adefovir elimination, 8 subjects will be enrolled from each of the
following age groups: 18-25 years and 48-55 years.